Serum Levels of Type 2 Chemokines in Lepromatous Leprosy Patients

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Serum Levels of Type 2 Chemokines in Lepromatous Leprosy Patients

Background: The type 2 deviated immunological state is predominant in lepromatous leprosy. Erythema nodosum leprosum (ENL) is an immune-complex mediated reaction that typically occurs in lepromatous leprosy. To date, the serum levels of tumor necrosis factor (TNF)-α, interleukin (IL)-2 receptor, IL-10, IL-1β, IL-1 receptor antagonist and monocyte chemoattractant protein-1 (MCP-1) were reported ...

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The serum concentrations of lactoferrin were determined by competitive enzyme immunoassay in the sera of 38 lepromatous leprosy patients and 16 healthy volunteers. Of the 38 lepromatous patients, 25 were without any sign of reactions while 13 were suffering from ENL type of reactions. The lactoferrin levels, in both types of patients, were observed to be significantly higher (P < 0.01 and < 0.0...

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Lepromatous leprosy of histoid type.

Histoid leprosy is a variant of lepromatous leprosy, which develops as a result of resistance to dapsone monotherapy. Here we report two cases of lepromatous leprosy of histoid type, one with typical and another with atypical presentations.

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Serum transaminase activity in lepromatous leprosy.

The semm transaminases COT (glutamate-oxalacetate-transaminase) and CPT ( glutamate-pyruvate-transaminase ), which have a determining share in intermediate metabolism, are present in the body ubiquitously and in an especially high concentration in heart muscle, liver or other parenchymatous organs and in skeletal muscle. The same is true for the serum dehydrogenase LDH (lactate-dehydrogenase) '...

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Objective: Vitamin D deficiency is a common disorder worldwide and is indicated by low serum 25-hydroxyvitamin D levels. Recent studies have suggested an association of 25-hydroxyvitamin D deficiency with diabetes mellitus. The objective of this study is to investigate the relationship between 25-hydroxyvitamin D concentration and type 2 diabetes in South Indian patients. Materials and Methods...

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ژورنال

عنوان ژورنال: Immune Network

سال: 2002

ISSN: 1598-2629,2092-6685

DOI: 10.4110/in.2002.2.4.223